Learning combinatorial transcriptional dynamics from gene expression data
نویسندگان
چکیده
منابع مشابه
Large-scale learning of combinatorial transcriptional dynamics from gene expression
MOTIVATION Knowledge of the activation patterns of transcription factors (TFs) is fundamental to elucidate the dynamics of gene regulation in response to environmental conditions. Direct experimental measurement of TFs' activities is, however, challenging, resulting in a need to develop statistical tools to infer TF activities from mRNA expression levels of target genes. Current models, however...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2010
ISSN: 1460-2059,1367-4803
DOI: 10.1093/bioinformatics/btq244